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PARP Enzymes and DNA Repair Research Beyond sirtuins, NAD+ is a critical substrate for poly(ADP-ribose) polymerases (PARPs), enzymes that detect and signal DNA damage, facilitating DNA repair processes
However, the therapeutic effects of GHK-Cu on UC have not been fully investigated
In the SEV group, B12 increased SAH ( P = 0.0091) and reduced SAM/SAH ( P = 0.0021)
doi: 10.1200/JCO.2015.63.5995 96 ShenBJiangHWangLQianJShuYChenPet al
