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And hydrogel systems offer sustained release formulations that could reduce dosing frequency from daily injections to weekly or even monthly administrations

USA 96 , 98739878 (1999)

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This may partly explain why conventional antioxidants or single-mechanism agents often show encouraging preclinical effects yet fail to achieve robust therapeutic efficacy in patients

However, not all are created equal

Understanding this dual role is critical for developing targeted therapies that selectively inhibit NF-B-driven tumor progression while preserving its anti-tumor immune functions