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When SIRT3 removes acetyl groups from isocitrate dehydrogenase 2 (IDH2), more NADPH gets made in mitochondria

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While the peptide might impact hormonal equilibrium and pathways related to ovulation and metabolic health, keep an eye on your hormones if you are considering it as part of a larger fertility protocol

The apparent lack of such a relationship for some drugs does not weaken the basic hypothesis but points to the need to consider the time course of concentration at the actual site of pharmacologic effect (see below)

REFERENCES Bergman K, Muller L, Weberg Teigen S

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