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Description
It is particularly important in acetaminophen overdoses where increasing GSH levels by supplementing the precursor N-acetylcysteine (NAC) is the treatment of choice to clear the toxic intermediate metabolite N-acetyl-p-benzoquinone imine (NAPQI) via conjugation [14]
[DOI] [PubMed] [Google Scholar] 108.Dreon M.S., Ceoln M., Heras H
[DOI] [PubMed] [Google Scholar] 488.Liu Y.-H., Alimujiang A., Wang X., Luo S.-W., Balamurugan S., Yang W.-D., Liu J.-S., Zhang L., Li H.-Y
The possible therapeutic effect of Se in HT to improve immune function was validated in a prospective study conducted in 2022, which showed that Se supplementation with 100ug per day improved thyroid function and the quality of life of patients by decreasing interferon gamma concentrations and increasing interleukin 1 concentrations (46)
With upregulated oxidative stress, malnutrition or increased toxic burden due to exposure to environmental contaminants, there can be even greater need for glutathione [7,8,9]
doi: 10.1002/art.22308 27 WilliamsJNChangSCSinnetteCMalspeisSParksCGKarlsonEWet al
