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In nervous tissue, where glutamate is present in concentrations higher than in the other tissues, GLUD1 appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification

We hypothesized that the perinuclear localization significantly increases the effectiveness of DNAzyme therapy, making it a good agent for perinuclear mRNA scanning and targeting after emerging from the nuclei through nuclear pores 56

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doi: 10.1111/jwas.12714 18 CapelliB.BagchiD.CysewskiG

Therefore, the absence of hematological abnormalities should not exclude the diagnosis of SCD

These compounds, derived from dietary sources, can modulate epigenetic pathways, promoting tumor cell apoptosis and inhibiting cell proliferation, invasion, metastasis, and cycle progression