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Figure 1 Iron metabolism is central to the regulation of ferroptosis, as iron plays dual roles in cellular physiology: it is essential for oxygen transport, DNA synthesis, and enzymatic reactions, yet its dysregulation drives pathological lipid peroxidation (Rochette, 2022)

Izadi A, Ebrahimi S, Shirazi S, Taghizadeh S, Parizad M, Farzadi L, Gargari BP

35,36 They can carry various cargo, including microRNAs (miRNAs), short noncoding RNA, proteins, DNA, messenger RNA (mRNA), nucleic acids and lipids

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The Dual Role of Glutamatergic Neurotransmission in Alzheimers Disease: From Pathophysiology to Pharmacotherapy

Because of this, predicting the consequences of neuropeptide release and/or activation can be difficult