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PPAR, -, and -, with PPAR being the primary cardiac transcriptional regulator of lipid homeostasis and the isoform most strongly implicated in DCM pathogenesis.26 PPAR exerts control over FA uptake, metabolism and storage through upregulation of genes coding for key proteins involved in these processes

10.1002/adma.202206286 51 NiuB.LiaoK.ZhouY.WenT.QuanG.PanX.et al (2021)

[PubMed: 26068959] 626

Free radicals actually attack and break down existing collagen fibers

10.1093/pcp/pcu179 Plant Cell Physiol

Lipid peroxidation results in the formation of lipid peroxides and various toxic byproducts, which lead to a cascade of cellular damage, ultimately impairing sperm function
