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Di Domenico F, Tramutola A, Barone E, Lanzillotta C, Defever O, Arena A, Zuliani I, Foppoli C, Iavarone F, Vincenzoni F, Castagnola M, Butterfield DA, Perluigi M

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Overall, changes in medium and longchain acylcarnitine concentrations are more strongly affected by the fasting and postprandial status of volunteers than by the intake of carnitine

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The findings consistently indicate no benefit and, in some cases, a worsening of CIPN with LC use

When activated by their ligands, such as 9-cis-retinoic acid, RXRs bind to specific response elements in target gene promoters, modulating transcriptional activity