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Accurate dosage is the key to getting reliable and reproducible results

For instance, lactate induces TGF-2 expression in glioma cells and knockdown of lactate dehydrogenase A (LDHA), an enzyme that catalyzes lactate production, downregulates TGF-2 levels ( TABLE 2 Modulation of TGF- signaling by metabolic changes

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For example, cadmium is recognized as a critical factor in the etiology of prostate and breast cancers

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These are known as isomers: R-lipoic acid and S-lipoic acid