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Elife 3 , e03245 (2014)

Metabolic diseases In addition to muscle and neurodegenerative conditions, alterations in NAD + levels and mitochondrial homeostasis are also observed in aging-associated metabolic diseases, particularly those conditions impacting highly mitochondrially-active tissues such as the kidney and liver 292294

Oral Supplements: Generally take longer to show noticeable results, especially if absorption is compromised

[3] Johansen PB, Hansen KT, Andersen JV, Johansen NL

Off-label use must be prescribed and supervised by a licensed provider

At 75mg daily, most protocols observe metabolic effects within 24 weeks