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Covalent inhibitors Covalent inhibitors contain an electrophile that is responsible for reacting with the enzyme to form a covalent bond
It was shown that the actual size of tumours determined by CT can be up to twice the size estimated at physical examination (McEntee, 2000
In the empatic-360 group, 82.6% of patients lost at least 5% of their baseline body weight and 47.7% lost at least 10% of their baseline body weight as compared to 18.9% and 5.7% patients in the placebo group, respectively [192]
