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ACMSD: a novel target for modulating NAD+ homeostasis

The downstream effects of NNMT inhibition by 5-amino-1MQ create a cascade of beneficial metabolic changes at the cellular level

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LL-37 and human beta-defensins LL-37 is the only human cathelicidin, produced by keratinocytes, neutrophils, and mast cells in the skin

This provides enough stimulation to maintain testicular volume and function without significantly elevating estrogen or causing other issues
