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The full metabolic picture takes about 6 months to stabilize

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A practical analogy is a time-release package that has to be opened inside the body before the medicine can do its job

doi: 10.18553/jmcp.2023.29.3.276 [DOI] [PMC free article] [PubMed] [Google Scholar] 16

This difference is attributed to its dual-agonist mechanism

In a recent news release, the manufacturer announced the submission of a new drug application to the US Food and Drug Administration (FDA) and a marketing authorisation application to the European Medicines Agency (EMA) for tirzepatide for the treatment of adults with type 2 diabetes [12]