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By inhibiting gastric acid production, PPIs reduce the acidity of chyme and allow the number of microbes in the small intestine to rise, causing small intestinal bacterial overgrowth (SIBO)

[DOI] [PubMed] [Google Scholar] 152.Schneiders W, Reinstorf A, Pompe W, Grass R, Biewener A, Holch M, et al

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1 Especially, for the skin wound, muscle, tendon, ligament and bone healing they obviously need various carriers in addition, and thereby, they could exert mostly a local effect

[DOI] [PubMed] [Google Scholar] 53.Brogna B., Amitrano M., Mangiacapra S., Gravino E., Capasso P.M.F., Gagliardi G., Musto L.A