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To address COPD induced by mitochondrial damage, a previous study employed BM-derived MSCs and exosomes (MSC + EXO) in a COPD mitochondrial Keima mouse model induced by acute cigarette smoke exposure over a period of 10 days (87)

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MDA accumulations were 1.2-fold higher in the EV and WT than in the TA (Figure 4C)

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Thats equivalent to taking roughly 150,000 cars off the road each year