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Domains assessed included randomization process, allocation concealment, blinding of participants and personnel, blinding of outcome assessment, incomplete outcome data, selective reporting, and other sources of bias

Medical Conditions Requiring Caution: Individuals with heart conditions Those with liver or kidney disease People with metabolic disorders Patients with Leber's disease (affecting the optic nerve) Those with low potassium levels (hypokalemia) [12] Pregnancy and breastfeeding present special considerations for MIC B12 treatment