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The development of collateral circulation will be influenced by the anatomic arrangements of vessels, the volume of ischemic tissue, the rate at which the vascular occlusion develops, the size of the occluded vessel, and, importantly, the quantity of blood flow, which is referable to the state of the systemic circulation, and the quality of blood flow, which is referable to such matters as the oxygen tension and viscosity of plasma

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The first-line treatment options for uncomplicated malaria are artemisinin-based combination therapies (ACTs)

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4 : 405414 Green DR and Kroemer G (2004) The pathophysiology of mitochondrial cell death