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Advanced glycation end products, their receptors and diabetic angiopathy

It has been shown to enhance the autophagylysosome pathway responsible for clearing misfolded proteins like -synuclein (38)

MALE INFERTILITY Research on male factor infertility demonstrates that sperm are vulnerable to reactive oxidative species (ROS) which can result in decreased motility (due to loss of mitochondria ATP production), decreased viability, increased mid-piece morphology, and reduced fertilization (sperm capacitation and acrosome reaction)
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Zhang L, Yan S, Zhang S, Yan P, Wang J, Zhang H (2021) Glutathione, carbohydrate and other metabolites of Larix olgensis A

However, attempts to reproduce these observations in other populations failed [7175]
