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doi: 10.1002/hep.27265
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Iron is a key cofactor for glutathione peroxidase 4 (GPX4), a lipid repair enzyme that neutralizes membrane lipid hydroperoxides to maintain RBC integrity (Rochette et al., 2022)
doi:10.1016/j.jaci.2009.11.017
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Metformin demonstrates antioxidative effects through diverse molecular pathways, including SIRT3 and AMPK pathway activation, restoration of paraoxonase activity, and downregulation of NADPH oxidase expression
