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Regular lab tests also track progress and ensure optimal therapeutic outcomes

To bridge this gap, more studies should focus on pre-clinical evaluations, moving towards clinical trials, and eventually integrating these findings into clinical practice

2 Materials and methods 2.1 Protocol and registration This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement (Moher et al., 2009) and the guidelines from the Cochrane Handbook for Systematic Reviews of Interventions (Supplementary Table S1

Journal of Clinical Endocrinology and Metabolism, 105(8), e2710-e2716

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Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming