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In nonresponsive cases, doctors can consider using parenteral B12, especially if oral B12 treatment has been used in the past or when serum vitamin B12 is not normalized (Table 2)
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"You have to show some evidence in people that the immune response that you're getting with the bivalent vaccine is clearly better, and those data haven't been presented," said Offit, an infectious disease and vaccine expert at Children's Hospital of Philadelphia
