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The effects were attributed to decreased BBB permeability, suppression of pro-inflammatory cytokines (TNF-a and IL-6), and modulation of excitatory and inhibitory neurotransmitter signalling [151]

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International Journal of Molecular Sciences, 19 (7), 1987.

The frequency of vitamin B12 injections depends on the underlying cause of the deficiency and the individuals medical needs

In some circumstances vitamin B-12 can cause the following side effects: Restenosis (reoccurrence of narrowing of a blood vessel) after stent placement / High blood pressure / Acne / Rash / Itchy or burning skin / Pink or red skin discoloration / Facial flushing / Urine discoloration / Numbness / Nausea / Difficulty swallowing / Diarrhoea / Increase in blood volume and red blood cells / Low potassium levels / Gout flare-up