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Silk fibroin-based nanoparticles for drug delivery

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The peptides were eluted onto an EASY-Spray HPLC column (Thermo ES902, ES903) using an Acclaim PepMap 100 (Thermo 164535) loading column and separated at a flow rate of 0.25 L/min

A decision from the agency could come as soon as late 2023, the drugmaker said

Additionally, proinflammatory cytokines TNF- and IL-1 were significantly reduced in the substantia nigra, with TNF-/GAPDH and IL-1/-actin ratios lowered by 4.5-fold and 14.1-folds, respectively, compared to untreated MPTP-mouse model

NEUHAUS, O.W., FLORY, W., BISWAS, N., & HOLLERMAN, C.E