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IV fluids were connected to run the normal saline infusion at 200 mL/hr
Histone H3K9la causes temozolomide resistance in glioblastoma by triggering the transcriptional repressor LUC7L2, which harms the DNA mismatch repair system (58)
doi: 10.1038/nature08097 100 DevadasSZaritskayaLRheeSGOberleyLWilliamsMS
Our recently conducted preclinical studies in the penetrating TBI animal model, demonstrated zero toxic effects for IP-administered NACA at the highest concentration (600 mg/kg), supporting a safer profile for its use as a mitochondrial-targeted neuroprotection compound for TBI (unpublished data)
A more negative potential promotes bond reduction
[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Tailor A., Meng X., Adair K., Farrell J., Waddington J.C., Daly A., et al
