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These findings highlight the therapeutic potential of SAMe and B-vitamins co-supplementation as a targeted metabolic strategy to mitigate ethanol-associated hepato-pancreatic injury

12 Cellular zinc homeostasis is delicately regulated by a network of proteins, which includes the solute carrier (SLC) families SLC30 (ZnT) and SLC39 (Zrt- and Irt-like proteins/ZIP), as well as the zinc-binding (MTs)

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doi: 10.1056/NEJMoa2510095 100 AdewaleATFalk LibbyEFuLLenzieABoitetERBirketSEet al

These substances are often sold as research use only products and may be self-administered or used in clinical environments despite limited human clinical data and unclear safety profiles