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Description
CN1 expression is encoded by the CNDP1 gene

Activated Akt then activates the mechanistic target of rapamycin complex 1 (mTORC1) via phosphorylation-mediated suppression of the tuberous sclerosis complex protein complex, which inhibits the small GTPase, Rheb, an essential activator of mTORC1

This phenomenon has prompted growing interest in the mechanisms that may underlie non-responsiveness to LT4 monotherapy

10.1016/j.jep.2022.115852 202 ZhangJ.XieS

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