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Researchers should note that AOD 9604s pharmaceutical development was discontinued due to insufficient efficacy findings in clinical trials, which is relevant context when evaluating either compounds utility in a research setting.

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A one-way ANOVA revealed an almost significant main effect of NNMT inhibitor treatment on intracellular NAD + levels (F (5,6) = 4.131, P = 0.0568) (Figure 3B)

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Notably, NNMTi did not affect food intake or cause any observed side effects