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This metabolic perturbation manifested as elevated methylglyoxal and 2-ketobutyrate alongside reduced L-cystathionine levels

Jia Q, Yang R, Liu X-F, Ma S-F

By contrast, acute-onset conditions such as ARDS, GVHD, and CRS showed relative low levels of DHT utilization both in numbers and in proportion terms

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(August 2025)

7 Conclusions and future perspectives DN is the leading cause of ESRD globally, its pathogenesis involving complex interactions among metabolic dysregulation, oxidative stress, inflammatory responses, and fibrotic pathways (Figure 6)