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B vitamin effects often persist several days to weeks

[DOI] [PMC free article] [PubMed] [Google Scholar] 138.Roginskaya M., Razskazovskiy Y
( Case description The patient was a 78-year-old man with dementia who lived for 16 years in Gypsum, Colorado at 6400 feet (1944 m, 0.79 ATA, 11.6 psi) and was a summertime vacation home neighbor of the primary author in Lake McConaughy, Nebraska (3330 feet altitude, 972 m, 0.89 ATA, 13.0 psi)

doi: 10.3390/ijms20030491
For example, a 2020 study found: Genetic predisposition to elevated serum IGF-1 levels was associated with higher risk of type 2 diabetes and coronary artery disease. The researchers note: Abnormal serum IGF-1 levels are associated with an increased risk of type 2 diabetes and cardiovascular diseasethe role of IGF-1 levels within the normal range in cardiometabolic disease remains unclear. 4
