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Nauseef, 2013)

Experimental series 1: effect of the apoE isoform on agonist induced neuronal cell death Neuro-2a cells were used to test apoE isoform specific effects from murine conditioned media on agonist induced neuronal death

DFO has demonstrated protective effects in SCI and IS, significantly reducing infarct size and improving neurological recovery in experimental models, though its short half-life limits clinical application (Yao et al., 2019

doi: 10.1016/j.tim.2020.02.004, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Dinat S., Orchard A., Van Vuuren S

Womens Midlife Health 4, 6

Peroxides, such as H 2 O 2 can trigger a two-electron oxidation of Hb leading to the formation of ferryl (Fe 4+ = O 2 ) Hb (Table 1, equation 2), whereas the reaction of metHb with H 2 O 2 yields ferrylHb radical (Hb + (Fe 4+ = O 2 )) in which the unpaired electron is associated with the globin or the porphyrin ring (Table 1, equation 3) (Harel and Kanner, 1988