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4 Alcohol and ER stress Cell damage can be caused not only by oxidative stress but also by ER stress, which acts as a secondary hit model for disease progression (73)

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Psychotherapies Medication (ketamine and/or antidepressants) alone might not cut it

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Iron not only produces ROS directly, but also participates in the synthesis of iron-containing LOXs that oxidize polyunsaturated fatty acids (PUFAs) to result in lipid peroxides (Lei et al., 2019)

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