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Proof-of-concept studies with fluorescent and confocal microscopy studies highlighted that the brain-targeted PLGA nanoparticles were able to cross the BBB and accumulated in neuronal cells, thus showing a promising brain drug delivery system

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Taurines role is also evident in multiple mental disease models and clinical studies: supplementation improves behavior deficits and significantly reduces social avoidance in CSDS-induced depression in C57BL/6 J mice (123)