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doi: 10.1080/14767058.2018.1555813 [DOI] [PubMed] [Google Scholar] 39.Frigeni M, Balakrishnan B, Yin X, Calderon FRO, Mao R, Pasquali M, et al

Number of Cells: 2

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This is consistent with a shunt of 3HIB or another intermediate from the muscle to the liver, rather than as a function of hepatic valine catabolism

Anti-inflammatory and anti-fibrotic mechanisms Although retatrutide treatment resulted in pronounced weight loss, prior studies have shown that obesity-associated immune, metabolic, and fibrotic signatures in epididymal adipose tissue can persist despite substantial weight loss, indicating that adipose tissue remodeling cannot be fully explained by weight loss [38, 39]

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