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Furthermore, a novel method using a combination of electron impact ionization (EI) and collision-induced dissociation coupled to GC/MS (GC-EI-MS) has been applied to accurately quantify the anti-aging lipid compound oleoylethanolamine (OEA) in nematodes, providing an excellent method for measuring the OEA dynamics under different genetic and environmental perturbations [232]

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We conclude that the mutation-induced defect in PGL-1 NtDD dimerization has a dominant-negative effect that reduces assembly of both PGL-1 and PGL-3 into granules, and that this likely explains the severe fertility defects of PGL-1 dimerization mutants

Rhyou H-I, Nam Y-H