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Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors
Nrf1 and c-Jun binds to both sites while Nrf2 binds only to the distal NFE2 site
Perinatology 40 (06), 612618
When interpreted together with the findings of the STEP 4 withdrawal trial and STEP 1 off-treatment extension study, which both showed weight regain after semaglutide discontinuation (after 20 weeks treatment in STEP 4 and 68 weeks treatment in STEP 1) 23,24 , these results support the benefit of continued semaglutide treatment for sustained weight loss
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