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Description
Monitor levels every 6 months given high-risk status
The molecule was developed by the Australian pharmaceutical company Metabolic Pharmaceuticals (in collaboration with Monash University) and advanced through Phase I safety trials and a Phase IIb obesity efficacy trial enrolling approximately 900 participants in total
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Some small studies suggest B12 (especially with B6) may reduce nausea, though more research is needed [*]
Risk of bias (RoB) scores, assessed using the NOS, ranged from 5 to 9 stars
[DOI] [PubMed] [Google Scholar] 42.Hornung T.C., Biesalski H.-K
