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This review is aimed at integrating the overwhelming progress made in the characterization of the physiopathological mechanisms of NAFLD at a molecular level, to better understand the factor influencing the initiation and progression of the disease

PMCID: PMC3972671

CLEC-2 is a transmembrane receptor that upon activation, homodimerizes and initiates Syk-dependent signaling of collagen receptor GPVI, platelet integrin IIb3, promoting platelet aggregation and thrombus formation (142144)

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