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Description
It is well-established that PTGS2, a gene that encodes cyclooxygenase-2 and determines the production of prostaglandin E2 (PGE2), is upregulated during ferroptosis in cancer cells
Detecting sequence homology at the gene cluster level with MultiGeneBlast
In addition, genetic suppression of phosphoglycerate dehydrogenase (PHGDH), a key enzyme in serine biosynthesis, compromises T cell expansion and antitumor immunity [141,145,146]
Wang, Y., Liu, X., Zhang, C
doi: 10.1016/s0079-6123(08)62691-6
Furin levels are high in salivary glands, liver, and bone marrow, whereas its expression is relatively low in muscle cells 334
