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doi: 10.1097/JCP.0b013e318217b4df

Other factors that have been reported to be prognostic include the histological subtype of the SCC, the location in the mouth (rostral neoplasms have a better prognosis), the maximum thickness of the neoplasm, the pattern of invasion of the neoplastic cells, lymphocyte infiltration of the neoplasm, and perineural and vascular invasion by the neoplastic cells

For APOC2 expression in macrophages, not only the ME.2 STAT1 site but also the STAT1 binding site in the proximal promoter confer macrophage-specific promoter activity

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