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DAMPs such as HMGB1, IL-33, and ATP released from liver injury bind to TLR2/4 and activate hepatic stellate cells (HSC), prompting their transformation into myofibroblasts and secretion of a large number of extracellular matrix proteins, which leads to matrix deposition and fibrosis [277, 316, 317]

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Data-independent acquisition (DIA) Proteomics assay Proteins were extracted using the SDT lysis buffer (4% SDS, 100 mM DTT, 100 mM Tris-HCl, pH 8.0) and then quantified

Metabolic Profiling of Cannabis Secondary Metabolites for Evaluation of Optimal Postharvest Storage Conditions

Finkelstein JD (1990)