glutathione dependent formaldehyde dehydrogenase Amino acid metabolism in mammals S-(hydroxymethyl)glutathione dehydrogenase - Wikipedia

Dimethyl fumarate protects neural stem/progenitor cells and neurons from oxidative damage through Nrf2-ERK1/2 MAPK pathway

GCLM (/)/hSOD1 WT mice do not spontaneously form tumors, their prepared fibroblasts exhibit elevated levels of ROS and DNA damage and upregulated levels of Tp53 and p21 (Hayes et al., 2020)

Fornasari D

This highlights the potential of targeting the ATOX1-TRAF4 axis as a novel therapeutic strategy for the treatment of atherosclerosis

Upon depolarization of astrocytes, molecules such as AQP4 that normally localize in endfoot membranes are redistributed to non-endfoot membranes, thereby compromising AQP4 function 24

However, higher doses can reduce the effects caused by oxidative stress and inflammation in COPD, demonstrating a positive impact on the rate of exacerbation [117]