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PMCID: PMC4664448 Luzgina NG, Potapova OV, Shkurupiy VA

For instance, high-mobility group box-1 (HMGB1) expression was found up-regulated in response to METH treatment and shown to mediate the neuroin?ammatory response in the nucleus accumbens, ventral tegmental, and prefrontal cortex of the brain (Thomas et al., 2008)

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any residual solution remaining after this interval, or if contamination is suspected, must be discarded in accordance with local pharmaceutical-waste regulations