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Regulatory agencies apply stricter benefit-risk thresholds for obesity treatments than for life-threatening conditions, and tesofensines stimulant-like cardiovascular effects did not meet that threshold despite producing 10% mean weight loss

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In its May 2026 public notice, the CDSCO made a definitive legal clarification under the Drugs and Cosmetics Act, 1940: products supplied in injectable form do not qualify as cosmetics under Indian law and cannot be marketed or used as such