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In: Advances in bone and mineral research annual II

A small amount is degraded in transit through the gastric mucosa, but most is catabolized in the liver, primarily by alcohol dehydrogenase (ADH) but also by cytochrome P-450 2E1 (CYP2E1) and the microsomal enzyme oxidation system (MEOS)

These conditions elevate urinary calcium and oxalate concentrations, fostering crystal formation and subsequent renal complications

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Drug Resist Updates 52:100712 Shi S et al (2016) ER stress and autophagy are involved in the apoptosis induced by cisplatin in human lung cancer cells