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Description
This process comprises encapsulating debris in double-membrane autophagosomes, followed by fusion of autophagosomes with lysosomes [248]
Matthes, D., Gapsys, V., Griesinger, C
Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, et al
doi: 10.1016/S0010-7824(02)00277-9 22 HuangY-YWuC-HLiuC-HYangS-FWangP-HLinL-Yet al
10.1007/s00520-016-3256-5 77 FlattersS
Another AD study, focused on targeting CD38, showed that CD38 knockdown in APP Swe mutation-expressing transgenic mice enhanced NAD + levels and reduced A plaques in brain extracts, mirrored by some improvement of cognitive performance 270,274
