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The presence of IgG3 has also been found to predict the treatment response to IVIg, which is thought to work at least partly by saturating FcRn and thereby preventing endogenous IgG from being salvaged from degradation [163, 164]

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1 There are lots of animal studies. Animal studies are useful for mechanism and early safety signals, but they do not prove that a treatment works in humans

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[DOI] [PubMed] [Google Scholar] 227.Redman LM, de Jonge L, Fang X, Gamlin B, Recker D, Greenway FL, et al

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