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Commun Biol 8 , 15 (2025)

Warner D

The transition state in catalysis by papain is shown on Fig

In this model, excess ROS plays a role in decreasing the expression of PKC II, as overexpression of GPx1 increases PKC II expression and ERK1/2 activation

It also activates pathways like Egr-1, NAB2, and JAK-2
