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A molecule of melatonin has a high capacity to scavenge several oxygen or nitrogen-derived radicals at one time and interact with both, receptor-dependent and -independent processes

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Thus, PGRMC1 dimerization is important for cancer cell proliferation and chemoresistance

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Indeed, P-15 was found to stimulate the proliferation and differentiation rate as well as the growth factor production of osteoblasts in vitro [113, 137, 189]