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177 However, all individuals with this jeopardy do not develop the disease, signifying that these inter-individual differences are products of interactions between genes and the environment

This resilience is attributed to the structural diversity of key defensive secondary metabolites in plants, including alkaloids, phenolics, and terpenoids

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Savic MM, Clayton T, Furtmuller R, Gavrilovic I, Samardzic J, Savic S, et al

For example, by inserting a 1059-bp DNA fragment into the upstream regulatory region of the rib operon of Lactiplantibacillus plantarum , the amount of riboflavin produced by the mutant strain will be higher than that of the wild type ( Lactococcus lactis JC017 mutant, purine starvation induced the overexpression of riboflavin biosynthesis cluster ribABGH , indicating that mutations that inhibit purine biosynthesis can trigger riboflavin secretion more effectively ( In addition to folic acid and riboflavin, lactic acid bacteria can also produce other types of vitamins

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