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Similarly, the exposure of human dopaminergic SH- SY5Y cells to rotenone caused the nuclear translocation of nuclear factor B (NF-B) and the activation of caspase-3, suggesting that complex I deficiency induced by rotenone can induce NF-B-mediated apoptosis (Figure 3) [68]
10.1074/jbc.RA120.013805 10.1074/jbc.RA120.013805 [DOI] [PMC free article] [PubMed] [Google Scholar] Li C, Qian T, He R et al (2021) Endoplasmic reticulum-plasma membrane contact sites: regulators, mechanisms, and physiological functions
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Demonstrated the function of Dnmt3 enzymes by studying both Dnmt3a and Dnmt3b knockout mice
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